Boltz-2 is a state-of-the-art model that builds on the general architecture of AlphaFold 3, predicting biomolecular structures and binding affinities.

BoltzGen is a system that builds on Boltz-2 and designs protein binders (potential drugs) to biomolecular targets.

We implement both systems on Tenstorrent hardware to make drug discovery more open, more efficient, and cheaper.

GitHub Repository: https://github.com/moritztng/tt-boltz My Thesis: https://moritztng.github.io/thesis/thesis.pdf